Jon Cryer might consider backing his “Two and a Half Men” co-star Charlie Sheen if Sheen were to somehow challenge President Donald Trump for political office.

Appearing on “The MeidasTouch Podcast” Wednesday, Cryer walked back his earlier comparison of Sheen and Trump while expressing his ongoing distaste for the current commander in chief.

“To be clear, as many of the issues that Charlie faces, I do think he’d be a better president,” he quipped. “So … I don’t know that it’s fair to completely lump the two of them together.”

Cryer made his headline-making assessment of Trump in 2016, when the future president was still a first-time candidate.

Watch a clip of Jon Cryer’s “MeidasTouch Podcast” chat below.

“I have been pointing out, and I have been screaming to the rooftops, that Donald Trump is the Charlie Sheen of politics,” the actor said during an appearance on the “Never Not Funny” podcast that year. “I love Charlie Sheen, I loved working with him when he was sober, but … he’s full of shit. He has been full of shit, he has serious addiction. His addiction is obviously serious … but Trump is just addicted to feeling important.”

In his “MeidasTouch Podcast” chat, Cryer clarified that any similarities between Sheen and Trump were simply in their communication styles ― at least at the time when Sheen was experiencing drug and alcohol addiction.

“The thing I was pointing out was that, at the time when I made that comment, Charlie was still just going off and saying whatever stupid ‘tiger blood’ comments he was making,” he explained. “And Trump has always been comfortable with saying whatever stupid thing he said, because people wrote him off as harmless and didn’t hold him responsible for those things.”

“Two and a Half Men” co-stars Charlie Sheen and Jon Cryer in 2009.

Jason Merritt via Getty Images

Cryer and Sheen portrayed brothers Alan and Charlie Harper, respectively, on CBS’s “Two and a Half Men” when the series premiered in 2003. While on set, Sheen and series co-creator Chuck Lorre famously clashed. In 2011, Sheen was fired from the show following its eighth season.

When the show’s ninth season premiered, the character of Charlie Harper was said to have died, with actor Ashton Kutcher joining the cast in the newly written role of billionaire Walden Schmidt.

In recent years, Cryer has shrugged off the suggestion of a reunion with Sheen, despite the latter having been more outspoken with regard to his experiences with addiction. In 2023, Sheen told People he’d been sober for six years.

“There was just instant evidence that this was the side I needed to be on. I couldn’t be in denial about it anymore,” he said at the time. “I’m proud of the choices that I’ve made and the changes I’ve made to live a life today that will never look like that mess. That was some alien version of myself.”

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